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Clinical Nutrition and Management

Evaluate the postprandial metabolic response, and cope with a disease!

Searching for management methods and food compositions that can contribute to the prevention / treatment of disease

"Nutrition management" is extremely important in prolonging healthy life span and treating diseases. Currently, this laboratory focuses on the evaluation of “diet composition” and “functional nutrient” for treatment and prevention of ectopic fats such as fatty liver, especially “postprandial” metabolic dynamics, differences in nutrient utilization and biological responses (including molecular mechanism). In addition, hyperphosphatemia has been reported to induce vascular dysfunction not only in dialysis patients but also in healthy people, and it is necessary to accurately grasp phosphorus intake. Using a 24-hour urine collection method, we are examining the contents of diets that are useful for grasping phosphorus intake and nutritional management. Furthermore, because there is insufficient evidence about the effects of nutritional guidance, research is being conducted at hospitals where joint research is conducted on teaching methods and management methods. With regard to knowledge and techniques that are useful in the clinical field, thinking power and practical ability, we are engaged in the training of high quality managed dietitians with "research ability" through research.


1. Research on the influence to the living body of the nutrient (or nutrient component) which suppresses postprandial hyperglycemia
2. Research on phosphorus intake using 24-hour urine storage and influence of eating behavior on serum FGF23 concentration
3. Research on the effect of long-term nutritional counseling for patients with hyperlipidemia (triacylglycerol and LDL cholesterol)
4. Research on diet therapy to prevent hyperphosphatemia
5. Research on the construction of diet therapy for hyperuricemia

Professor

Hidekazu AralPhD, Prof.
arai@u-shizuoka-ken.ac.jp
TEL.+81-54-264-5511

Professor

Yuka KAWAKAMIPhD, Research Asst. Prof.
TEL.+81-54-264-5596

Details are here

http://sfns.u-shizuoka-ken.ac.jp/nutrcont/

 

Figure.1

Correlation between dietary record and 24-h urine collection. Correlation between dietary record (DR) and 24-h urine collection (UC) for protein (A) and phosphorus (Pi) (B).

Figure.2

Change in serum TG levels by counseling for 12 months in the dietary and combined drug treatment groups. Red triangle, dietary counseling alone group (n=47); Blue circle, combined drug treatment group (n=12).

References

  1. Endocr J. in press (2019)
  2. J Med Invest. 66, 134-140. (2019)
  3. J Atheroscler Thromb. 26, 39-49. (2019)
  4. J Clin Biochem Nutr. 62, 259-263 (2018)
  5. J Clin Biochem Nutr. 60, 125-129. (2017)
  6. Nutr J. 14:106. (2015)
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